Correlation of apelin with microalbuminuria in type 2 diabetic patients

نویسندگان

چکیده

Abstract Introduction. Type 2 diabetes mellitus is the root cause of diabetic nephropathy, a condition affecting kidneys (T2DM). The number people who have type growing. Aim. To evaluate differences in Apelin 13 levels between patients with T2DM had normal or microalbuminuria and those microalbuminuria, as well these healthy controls. intent to better understand its link microalbumin, haemoglobin A1c, insulin resistance (IR), other standard measures. Materials methods. Sixty individuals diabetes, aged 35 45, were selected, their normoalbuminuria compared. Thirty age-matched volunteers selected serve concentrations plasma measured ELISA kits. Turbilatex assay was used calculate microalbumin concentrations. Measurements glycosylated (HbA1C) made via high-performance liquid chromatography. Results. Patients higher protein than did different from normoalbuminuric another important way. Correlations albuminuria, HbA1c, HOMA-IR all positive. Conclusion. Considering that critical risk factor frequently arises early stages it may be useful for assessment vascular issues patients.

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ژورنال

عنوان ژورنال: Current Issues in Pharmacy and Medical Sciences

سال: 2023

ISSN: ['2084-980X', '2300-6676']

DOI: https://doi.org/10.2478/cipms-2023-0009